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In a very recent study, we claimed the identification and also the characterization of a completely new atypical opioid receptor with special destructive regulatory Qualities toward opioid peptides.1 Our effects showed that ACKR3/CXCR7, hitherto known as an atypical scavenger receptor for chemokines CXCL12 and CXCL11, can be a wide-spectrum scaveng